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Strategies for Responding to a Warning Letter

Attorney Nick Oberheiden lays out a 10-step strategy for companies to use in responding to an FDA Warning Letter.

Biologics

Breakthrough on Pfizer RSV Vaccine

FDA grants Pfizer a breakthrough therapy designation for its respiratory syncytial virus (RSV) vaccine candidate, PF-06928316 or RSVpreF, and its use ...

Federal Register

Oncology Trial Master Protocols Guidance

Federal Register notice: FDA makes available a final guidance entitled Master Protocols: Efficient Clinical Trial Design Strategies to Expedite Develo...

Human Drugs

Stakeholder Suggestions for FDA Registries RWD Guidance

Four stakeholders make suggestions for an FDA draft guidance on using registries as part of real-world data in drug and biologic regulatory decision-m...

Human Drugs

Finch Phase 3 C. Diff Trial Still on Hold: FDA

FDA says its clinical hold on a Finch Therapeutics Phase 3 trial of CP101 remains in place as the company responds to a request for information on its...

Human Drugs

FDA Finalizes PLAIR Guidance

FDA publishes a finalized 2013 draft guidance on pre-launch activities importation requests.

Federal Register

Guide on Oncology Expansion Cohorts

Federal Register notice: FDA makes available a final guidance entitled Expansion Cohorts: Use in First-in-Human Clinical Trials to Expedite Developmen...

Human Drugs

FDA Hold on Celyad Oncology Trial

FDA puts a clinical hold on a Ceylad Oncology Phase 1b trial due to insufficient information to assess the risk to study subjects.

Former FDAer Wants Freeze on Russian Applications

Former FDAer Timothy Cote asks FDA to suspend regulatory actions on all requests it has from Russian pharmaceutical and medical device companies.

Human Drugs

FDA-483 from OSRX Inspection

FDA releases the FDA-483 with one observation issued following an inspection at OSRX, a Missoula, MT, sterile drug compounder.