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Human Drugs

Petition Wants 2 Cassava Simufilam Trials Halted

Attorney Jordan Thomas asks FDA to halt clinical trials of Cassava Sciences simufilam until the agency thoroughly evaluates the scientific support for...

Federal Register

Panel to Review Prader-Willi Syndrome NDA

Federal Register notice: FDA announces an 11/4 Psychopharmacologic Drugs Advisory Committee meeting to discuss a Levo Therapeutics NDA for Prader-Will...

Human Drugs

FDA Orders New Warning on JAK Inhibitors

FDA orders a drug class warning for Janus kinase inhibitors after reviewing a recent clinical trial that showed an increased risk of serious heart-rel...

Human Drugs

Ranitidine Products May Return to Market: FDA

FDA says it may approve returning ranitidine-containing products to the market based on new CDER research into the carcinogen NDMA.

Human Drugs

AnazaoHealth Compounding Unapproved Drugs: FDA

FDA warns AnazaoHealth that it is compounding drugs that do not meet legal requirements and are considered to be misbranded unapproved new drugs.

Human Drugs

Astellas Pauses ASPIRO Trial

Astellas pauses screening and dosing additional participants in its ASPIRO trial of an investigational gene therapy.

Biologics

Woodcock Attempts to Quell CBER Dissent

FDA acting commissioner Janet Woodcock weighs in on the announced departures of two senior CBER vaccine officials, pledging support and asserting conf...

Medical Devices

Asensus Surgical Laparoscopy Device Enhancements Cleared

FDA clears an Asensus Surgical 510(k) to expand the machine vision capabilities of its previously cleared Intelligent Surgical Unit (ISU).

Human Drugs

Merck Gains Keytruda Full Approval in Bladder Cancer

FDA converts Mercks accelerated approval to full approval for its anti-PD-1 Keytruda (pembrolizumab) and its use in first-line treatment of advanced b...

FDA General

DoJ Changes 2 Guidance Policies: Attorneys

Attorneys Anne Walsh and JP Ellison describe changes to two Justice Department policies on using guidance documents in enforcement actions.