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FDA General

Draft Guide on PD-1, PD-L1 Alternative Dosing

Federal Register notice: FDA makes available a draft guidance entitled Pharmacokinetic-Based Criteria for Supporting Alternative Dosing Regimens of Pr...

Human Drugs

FDA Approves Expanded Age for Ironwoods Linzess

FDA approves a revised label for Ironwoods Linzess expanding the potential for off-label use in children under age 18.

Medical Devices

Court Tosses Boston Scientific Whistleblower Case

Three Sidley Austin attorneys describe a Minnesota federal court decision rejecting a whistleblowers claims that Boston Scientific fraudulently induce...

FDA OKs Expanded Tibsovo Indication Plus Diagnostic Test

FDA approves an expanded indication for Serviers Tibsovo plus a companion diagnostic test to identify patients for the new indication.

Human Drugs

Takeda Illegally Extended Actos Patents: Court

The 2nd Circuit Appeals Court says antitrust suits alleging that Takeda illegally delayed generic entry of its diabetes drug Actos can continue.

Medical Devices

Fuse Medical 510(k) for Knee System

FDA clears a Fuse Medical 510(k) for its Tibial Revision Knee System and the PS Plus Posterior Stabilized Tibial Insert.

Human Drugs

10 Observations on Fujifilm Diosynth FDA-483

FDA releases an FDA-483 with 10 observations from an inspection at the Fujifilm Diosynth Biotechnologies drug substance manufacturing facility.

Medical Devices

FDA Warns UK Face Mask Marketer

FDA issues a Warning Letter to Invisi Smart Technologies (United Kingdom) over its Invisi Smart Mask for sale in the U.S. without a cleared 510(k).

Human Drugs

Amneal Plans Parkinsons NDA for IPX-203

Amneal Pharmaceuticals says it will file an NDA for IPX-203 in mid-2022, after reporting positive topline results from a Phase 3 clinical trial that e...

Federal Register

eCTD Submisson Rejections Due to Validation Failures

Federal Register notice: FDA announces that beginning 3/1/2022 it will reject Electronic Common Technical Document submissions that fail validations 1...