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Human Drugs

FDA Approves Expanded Xarelto Indication

FDA approves an expanded indication for Janssens Xarelto to include patients with recent lower extremity revascularization under specific circumstance...

Human Drugs

7 Observations in Jubilant Generics FDA-483

FDA released the FDA-483 with seven observations from an inspection at Indias Jubilant Generics drug manufacturing firm.

Human Drugs

FDAers Boost Viral Clearance in Continuous Manufacturing

FDA says CDER researchers have developed a three-step process to promote viral clearance during continuous manufacturing of therapeutic proteins.

Human Drugs

Senators Want Info on FDA Relationship with McKinsey in Opioid Crisis

A bipartisan group of six senators quizzes FDA on the potential conflicts of interest in agency contracts with McKinsey since the consulting firm also...

Human Drugs

CGMP Violation Found in Toyobo Inspection

FDA warns Japans Toyobo Co. about a CGMP violation in its manufacturing of finished drugs.

Federal Register

Guide on ANDA Bioequivalence Studies

Federal Register notice: FDA posts a draft guidance entitled Bioequivalence Studies With Pharmacokinetic Endpoints for Drugs Submitted Under an ANDA....

Human Drugs

Industry Seeks Changes to Cancer Trials PROs Guidance

In comments to FDA, drug companies and industry organizations urge the agency to develop additional and broader guidance on patient-reported outcomes.

Human Drugs

Alexion Scraps Ultomiris ALS Trial

Citing a lack of evidence, AstraZenecas Alexion drug unit discontinues its CHAMPION-ALS Phase 3 clinical trial of Ultomiris (ravulizumab) in adults wi...

Medical Devices

Cardinal Health Recalls Saline Syringes

Cardinal Health recalls three models of its Monoject Saline Flush Prefilled Syringes because their plunger may pull air into the syringe after a healt...

Biologics

FDA Approves Pfizer-BioNTech Vaccine

FDA approves the first Covid-19 vaccine Pfizer-BioNTechs vaccine that is now under the trade name Comirnaty.