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Human Drugs

Janssen NDA for Pediatric Use Xalrelto

Janssen Pharmaceutical files an NDA for Xarelto (rivaroxaban), seeking its use in pediatric patients.

Federal Register

BLA Chemistry, Manufacturing and Control Changes Guide

Federal Register notice: FDA makes available a final guidance entitled Chemistry, Manufacturing, and Controls Changes to an Approved Application: Cert...

Human Drugs

Advisors Asked Whether to Delay Incyte Cancer Drug Deliberation

FDA asks the Oncology Drugs Advisory Committee to assess whether there is sufficient clinical trial data on Incytes retifanlimab to take regulatory ac...

Human Drugs

Consider Exploring EOP2 Loophole: Attorney

Attorney Josephine Torrente says drug sponsors disagreeing with FDA over a Phase 3 protocol have no right of appeal and could consider using a special...

Human Drugs

Firm Selling Misbranded, Unapproved New Drugs: FDA

FDA warns Molecular BioLife it is marketing misbranded unapproved new drugs via a Web site.

FDA General

Ex-FDA Chief Counsel Joins Morrison & Foerster

Former FDA chief counsel Stacy Cline Amin joins Morrison & Foerster as a partner in its life sciences/healthcare practice.

Human Drugs

Agios Pharma NDA for Pyruvate Kinase Deficiency

Agios Pharmaceuticals files an NDA for mitapivat for treating adults with pyruvate kinase deficiency.

Human Drugs

Review of Drug Trials with External Controls

Researchers say FDA guidance on external controls in drug trials should be revised to reflect the use of retrospective natural history studies.

Federal Register

EUA for B. Brauns Propofol-lipuro

Federal Register notice: FDA announces for administrative purposes the issuance of an emergency use authorization to B. Braun Melsungen AG and the use...

Federal Register

Reg Review Period for Alnylans Givlaari

Federal Register notice: FDA determines for patent extension purposes the regulatory review period for Alnylam Pharmaceuticals Givlaari (givosiran).