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FDA Signals Pragmatic Push to Ease Biosimilar Development

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FDA Office of Therapeutic Biologics and Biosimilars director Sarah Yim says the agency is focused on making biosimilar development...

BioMarins sBLA for Palynziq for Expanded Use

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FDA accepts for priority review a BioMarin Pharmaceutical supplemental BLA for Palynziq (pegvaliase-pqpz) to expand the therapys u...

Rare Cancer Seamless Clinical Trials

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A Friends of Cancer Research working group white paper makes the case for seamless clinical trials for rare cancers.

Revolution Medicines Wins Orphan Drug Status

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FDA grants Revolution Medicines an orphan drug designation for its investigational therapy daraxonrasib for treating pancreatic ca...

Regeneron Gets Complete Response on Eylea sBLA

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FDA sends Regeneron a complete response letter for its pre-filled Eylea HD syringe supplemental BLA, citing unresolved inspection ...

Multiple Violations at 3 Royal Philips Facilities

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FDA warns Royal Philips, based in the Netherlands, about multiple violations at two of its U.S. medical device manufacturing facil...

Unicycive Plans OLC NDA Resubmission This Year

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Unicycive says it plans to resubmit its NDA for oxylanthanum carbonate to treat hyperphosphatemia before the end of this year.

4 Repeat CGMP Violations at Canadas Innocore

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FDA warns Innocore Sales & Marketing in Woodstock, Ontario, Canada, about CGMP violations in its production of finished drugs.

OND Deputy Named Permanent Director

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FDA names acting Office of New Drugs (OND) director Mary Tran Thanh-Hai as the new OND director, replacing previous head Peter Ste...

Is FDA Lengthening Warning Letter Response Time?

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Three Hyman, Phelps & McNamara attorneys notice that FDA has provided a 30-day response time instead of the usual 15 days for two ...