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1st Cycle NDA Approvals Fall in 2024: CDER

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A CDER drug approval reports shows that first-cycle NDA approvals fell in 2024 to 74% (37 of the 50 novel drugs approved) from 84%...

FDA Sees Challenges in Condoliase BLA

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FDA asks members of its Anesthetic and Analgesic Drug Products Advisory Committee to discuss several challenges the agency has ide...

Vanda Criticizes FDA Over Drug Rejection

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Vanda Pharmaceuticals criticizes FDA for failing to approve the companys NDA for tradipitant to treat the symptoms of gastroparesi...

Annes Daye Pulls CBD Tampons in U.S.

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Annes Daye says it is pulling its CBD-coated tampons from the U.S. market following receipt of an FDA Warning Letter.

Optical Imaging Drug Development Guidance

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FDA publishes a draft guidance on developing drugs for optical imaging for three purposes.

Dizal Lung Cancer NDA Accepted for Priority Review

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FDA accepts for priority review a Dizal NDA for sunvozertinib, an oral EGFR inhibitor for treating locally advanced or metastatic ...

5 Repeat CGMP Violations at Indoco Remedies

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FDA warns Indias Indoco Remedies about repeat CGMP violations in its production of finished drugs.

FDA Obesity/Overweight Drug Development Guide

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FDA publishes a draft guidance with recommendations on clinical trials for drugs and biologics to treat obesity and overweight.

Off-Label Communications Q&A Guide

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FDA issues a guidance finalizing a 2023 draft document on communicating scientific information on unapproved uses of approved or c...

Rybrevant/Lazcluze Cancer Study Positive: J&J

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Johnson & Johnson says its Phase 3 MARIPOSA study showed that its Rybrevant (amivantamab-vmjw) plus Lazcluze (lazertinib) had a st...